The OneK1K cohort consists of single-cell RNA sequencing (scRNA-seq) data from 1.27 million peripheral blood mononuclear cells (PMBCs) collected from 982 donors. We developed a framework for the classification of individual cells, and by combining the scRNA-seq data with genotype data, we mapped the genetic effects on gene expression in each of 14 immune cell types and identified 26,597 independent cis–expression quantitative trait loci (eQTLs).
Update - 2023/11/13
We regret to inform you that the OneK1K eQTL Browser is temporarily unavailable, and we apologise for any inconvenience caused. In the meantime, the results are available for download below. If you have any questions, please contact us via this form.